My expertise is the development and application of statistical techniques to the quantitative analysis of large, high-dimensional data sets. The results of my academic analyses in the fields of genetics and neuroscience have contributed to a better understanding of a wide range of natural phenomena, including multiple sclerosis, cholesterol levels, body shape, nausea, fear, visual perception, gene expression, and the interaction of genetics with life experience.
A summary of my research is available on my Oxford University research webpage. I enjoy presenting my findings to technical and lay audiences alike, and have been recognised for my talks at international events. My doctoral dissertation, on statistical techniques for uncovering the genetic basis of behaviour, is freely available for download with or without appendices.
Key Publications
- Baud, Mulligan, Casale, et al. (2017). Genetic variation in the social environment contributes to health and disease. PLOS Genetics 13: e1006498 [covered by BBC, Sun, Daily Mail, Live Science, Le Temps, and the European Bioinformatics Institute]
- Krohn, Rives-Corbett, Donner (2016). Predicting Job Application Success with Two-Stage, Bayesian Modeling of Features Extracted from Candidate-Role Pairs. In Proceedings of the Joint Statistical Meetings, Section for Statistical Learning and Data Science: 3667-3671
- Krohn, Speed, Palme, et al. (2014). Genetic interactions with sex make a relatively small contribution to the heritability of complex traits in mice. PLOS ONE 9: e96450
- Agakov, McKeigue, Krohn, Storkey (2010). Sparse Instrumental Variables (SPIV) for genome-wide studies. Advances in Neural Information Processing Systems 23 (Edited by: Lafferty et al.)
Additional Publications
- Taylor, Martin, Lise, et al. (2015). Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. Nature Genetics 47: 717-26
- Randall, Winkler, Kutalik, et al. (2013). Sex-stratified genome-wide association studies in 270,000 individuals show evidence for sexual dimorphism in genetic loci for anthropometric traits. PLOS Genetics 9: e1003500
- Agakov, Krohn, Colombo, McKeigue (2011). Sparse instrumental variables: an integrative approach to biomarker validation. Journal of Epidemiology and Community Health 65: A10
- Chen, Krohn, Bhattacharya, Davies (2011). A comparison of exogenous promoter activity at the ROSA26 locus using a PhiC31 integrase mediated cassette exchange approach in mouse ES cells. PLOS ONE 6: e23376
- Agakov, McKeigue, Krohn, Flint (2011). Inference of causal relationships between biomarkers and outcomes in high dimensions. Journal of Systemics, Cybernetics and Informatics 9: 1-8
- Orton, Wald, Confavreux, et al. (2011). Association of UV radiation with multiple sclerosis prevalence and sex ratio in France. Neurology 76: 425-31
- Limebeer, Krohn, Cross-Mellor, et al. (2008). Exposure to a context previously associated with nausea elicits conditioned gaping in rats: A model of anticipatory nausea. Behavioural Brain Research 187: 33-40
